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structure & organization

Professor Sir Dr Magdi Yacoub

Director of Research

Professor Sir Magdi Yacoub is Professor of Cardiothoracic Surgery at the National Heart and Lung Institute, Imperial College London and Founder and Director of Research at the Magdi Yacoub Heart Centre. Professor Yacoub is also the Founder and Director of Research at Harefield Heart ScienceCentre (The Magdi Yacoub Institute) overseeing over 60 scientists and students in the areas of tissue engineering heart valves, myocardial regeneration, novel left ventricular assist devices, stem cell biology, end stage heart failure and transplant immunology. Professor Yacoub was born in Egypt and graduated from Cairo University Medical School in 1957, trained in London and held an Assistant Professorship at the University of Chicago. He is a former BHF Professor of Cardiothoracic Surgery for over 20 years and Consultant Cardiothoracic Surgeon at Harefield Hospital from 2001-1969 and Royal Brompton Hospital from 2001-1986. Professor Yacoub established the largest heart and lung transplantation programme in the world where more than 2,500 transplant operations have been performed. He has also developed novel operations for a number of complex congenital heart anomalies. A world pioneer in heart surgery, Professor Yacoub received the highest award possible from Her Majesty Queen Elizabeth in 2014, the Order of Merit, for his services to humanitarian work and the fight against cardiovascular disease. He was knighted for his services to medicine and surgery in 1991 and awarded the Fellowship of the Academy of Medical Sciences in 1998 and Fellowship of the Royal Society in 1999. A lifetime outstanding achievement award in recognition of his contribution to medicine was presented to Professor Yacoub by the Secretary of State for Health in the same year. In Egypt, Professor Yacoub was awarded the order of the Nile in 2011, the highest state honour. Dedicated to global healthcare delivery, Sir Magdi founded the Chain of Hope in 1995 treating children with correctable cardiac conditions from war-torn and developing countries and establishing training and research programmes in local cardiac units

Yasmine Aguib, Dr. rer. nat.

Deputy Director, Life Sciences & Molecular Research

Yasmine Aguib holds a Masters and a Doctoral Degree in Molecular Medicine and Biotechnology from the Technische Universität München (Germany) and is heading the Life Sciences Department at the Aswan Heart Centre – Magdi Yacoub Foundation. She holds an Honorary Research Fellowship at the National Heart and Lung Institute, Imperial College London – UK, is Young Co-PI in the Fondation Leducq Transatlantic Networks of Excellence for ‘Redox Regulation of Cardiomyocyte Renewal’ and adjunct Professor at the American University in Cairo. Dr. Aguib has received several awards, such as the DAAD Fellowship for Young Researchers, the Presidential Science & Engineering Research Fellowship and the Governor’s Award for Distinguished Research. She worked in the field of Protein Engineering, where she contributed to the design of bispecific antibodies for cancer therapy in collaboration with Pieris GmbH. Afterwards she focused on understanding molecular mechanisms of Proteinopathies and neurodegenerative diseases in frame of the Special National Research Program SFB 596 in collaboration with the LMU, Rocky Mountain Labs, Novartis, and the Mizushima Lab with a special focus on the role of Autophagy and related mechanisms. In frame of the German Excellence Initiative she was appointed scientific consultant to the TUM president in the fields of life sciences and international strategic alliances where she contributed to the establishment of the TUM.Global Strategy and the EuroTech Universities Alliance. She is also a member of the Advisory Board Member of the Biology Department at the American University in Cairo. In her role as a Deputy Director for Life Sciences Research at the AHC, she is contributing to the implementation and execution of AHC Research Strategy. Together with the Life Sciences Team, she focuses on understanding the role of molecular determinants of Heart disease, its etiology and manifestation in the Egyptian and North African population and on contributing to the advancement of genomic CV medicine in Africa and globally.

Heba Aguib, Dr. Ing.

Deputy Director of Biomedical Engineering & Innovation Laboratory

Heba Aguib holds a doctoral degree in Mechanical Engineering and is heading the Biomedical Engineering and Innovation Laboratory at the Aswan Heart Centre (AHC) – Magdi Yacoub Foundation, Egypt. She is Deputy Director of Research in Biomedical Engineering at AHC, Honorary Research Fellow at the NHLI - Imperial College London, UK, and Adjunct Professor at The American University in Cairo, Egypt. Dr. Aguib studied Mechanical Engineering at Technische Universität München (TUM) with a focus on Numerical Simulation and Automotive Engineering, and worked at the Department of Aerodynamics - BMW AG, Munich, on shape optimization using Computational Fluid Dynamics (CFD). She acquired her PhD in the field of Micro and Medical Device Technology. She joined the Robotics Group and together with several teams, she was developing adaptive mechanisms for tissue manipulation using Finite Element Methods (FEM) and Additive Manufacturing; in collaboration with Karl STORZ Endoskope, ETH Zürich and IRCAD at Hôpitaux Universitaires in France. She received the Cultural Award of Bavaria for Science 2011 for “Excellent Scientific Research” and a DAAD scholarship for Young Scientists (2002-2007). Before joining AHC, Dr. Aguib was Deputy Managing Director at Technische Universität (TU) Berlin, and played a major role in inaugurating the 1st campus of a German university in the region. Currently, she is a member of the BMW Responsible Leaders Network and the Global Diplomacy Lab. Dr. Aguib contributed to establishing the AHC Research Department, and is aligning projects and executing strategy with Prof Sir Magdi Yacoub. Together with an interdisciplinary engineering team, national and international partners, she is utilizing a broad spectrum of HighTech engineering skills to support advancing diagnosis and treatment in Cardiovascular Disease - by developing novel computational models and algorithms.

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Research Ethics Committee

The AHC Research Ethics Committee (AHC-REC) is an independent authoritative entity that is committed to ensure and promote ethical research at AHC through:

  • Protecting the rights and safety of human participants in research studies.
  • Performing risk benefit analysis of submitted research
  • Enforcing participants’ confidentiality
  • Assuring compliance with legal and institutional guidelines
  • Ensuring that informed written consent is collected from research subjects

All research proposals and research related documents are submitted to the AHC-REC for the latter to assess the compliance with ethical standards and the adequate protection for human participants in the research.

The AHC-REC is registered with the Egypt Ministry of Health, the US Department of Health and Human Services (HHS) Institutional Review Board (IRB) and the Federal wide Assurance for the Protection of Human Subject (FWA)